The Association between The Thickness of the Endometrium at the Day of Human Chorionic Gonadotrophin Injection and the Outcome Intracytoplasmic Sperm Injection

Abstract

Background: Clinically during ICSI, controlled ovarian stimulation (COS) is a famous way to increase
the number of mature oocytes picked up. This method must be asseeed with a substantial danger of ovarian
hyper stimulation syndrome (OHSS), which occurred if follicular induction is very strong. Along with
multifollicular growth, COS is also resulting in increased serum concentration of estradiol (E2) that in
turn may has effect on the receptivity of the endometrium .The high serum E2 concentration through COS
may resulting either with an increased chance of pregnancy or an impaired reproductive score secondary to
change in endometrial receptivity. Aim of the study: to assess the impact of thickness of the endometrium
at the day of hCG administration on the winning of intracytoplasmic sperm injection (ICSI) cycles. Patients
and method: A retrospective study in which 235 women who were undergo one time of ICSI cycle were
evaluated in this retrospective study, All patients were treated with gonadotrophin agonist either short or
long protocol. The patients were according to endometrial thickness they were categorized into three groups
I (<7mm), II (7-14mm), and group III (>14mm). Results: the rate of clinical pregnancy was increased ingroup II (7-14mm) than other two groups depending on endometrial thickness measurement.
Conclusion: endometrial thickness 7-14mm is associated with higher rate of clinical pregnancy