Liquid Biopsies in Cancer Diagnosis

Authors

  • R.Sharmila1 , Anitha Roy2 , K. Anjaneyulu3 , Lakshmi.T4

DOI:

https://doi.org/10.37506/ijfmt.v14i4.12457

Keywords:

Liquid biopsy, cancer, exosomes, circulating tumor cells, circulating tumor DNA, oncology.

Abstract

Over many years, the concept of precision medicine has dramatically renewed the sphere of clinical
oncology; the advent of patient-tailor-made therapies has appreciably stepped forward all measurable
outcomes. Liquid biopsy is a modern method that commences unexpected perspectives. It includes the
detection and isolation of circulating tumor cells, circulating tumor DNA and exosomes, as a supply of
genomic and proteomic records in patients with most cancers. Many technical hurdles had been resolved to
newly advanced techniques and subsequent-generation sequencing analyses, permitting a wide software of
liquid biopsy in a huge variety of settings. Initially correlated to analysis, liquid biopsy facts at the moment
are being studied for cancer analysis, with a bit of luck consisting of screenings, and most significantly
for the prediction of reaction or resistance to given remedies. In specific, the identification of particular
mutations in genes can be useful resources in therapeutic choices, both in the appropriateness of remedy and
within the superior identity of secondary resistance, aiming to early diagnose disease progression. Still, the
utility is far from fact however ongoing research is leading the manner to a new era in oncology. The main
aim of this study is to assess the importance of liquid biopsy in cancer diagnosis.

Author Biography

  • R.Sharmila1 , Anitha Roy2 , K. Anjaneyulu3 , Lakshmi.T4

    1Research Associate, Dental Research Cell, 2Associate Professor, Department of Pharmacology, 3Reader,
    Department of Conservaive Dentistry and Endodontic, Saveetha Dental College and Hospitals,, Saveetha Institute
    of Medical and Technical Sciences, Saveetha University,, Chennai-77, India, 4Associate Professor, Department of
    Pharmacology, Saveetha Dental College, Saveetha University, Chennai, India

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Published

2020-10-29

How to Cite

Liquid Biopsies in Cancer Diagnosis. (2020). Indian Journal of Forensic Medicine & Toxicology, 14(4), 5319-5327. https://doi.org/10.37506/ijfmt.v14i4.12457