Role of Oestrogen and Testosterone in Male Infertility

Authors

  • Archana Dhok1 , Ranjit Sidram Ambad2 , Sanjay Deshpande3 , Ninad Nagrale4

DOI:

https://doi.org/10.37506/ijfmt.v14i4.12603

Keywords:

Infertility, oestrogen, Testosterone, estradiol, gametogenesis.

Abstract

Introduction: About 15% of couples are infertile. This suggests they can’t think about a child, in spite of the
way that they’ve had visit, unprotected sex for a year or more. In over 33% of these couples, male barrenness
accept a role. Male infertility is a direct result of low sperm creation, unusual sperm limit or blockages that
forestall the movement of sperm. Afflictions, wounds, interminable clinical issues, lifestyle choices and
various parts can expect a job in causing male barrenness. Testosterone and Estrogen have been viewed as
male and female sex hormones, separately. However, estradiol, the dominating type of Estrogen, likewise
assumes a critical role in male sexual capacity. Estradiol in men is fundamental for modulating libido,
erectile capacity, and spermatogenesis.
Aim: Role of Eestrogen and Teststerone in Male Infertility.
Material and Method: The present study includes total 60 subjects that include 30 infertile male and 30
fertile male. Blood samples collected from the subjects were obtained for serum estrogen and testosterone
estimation, from OPD, general medicine and OBGY wards.
Result: As we found the level of oestrogen in infertile male was 19±1.2 as compared to fertile male
37.1±2.7pg/ml that is statistically highly significant. The degree of testosterone in infertile male was
4.94±0.98 while in fertile male it was 5.01±1.31 and it is statistically non-significant.
Conclusion: concentrations of serum estradiol in infertile patients are reduced significantly. It remains to
be explained why estradiol decreased. Based on our results, however, there is little benefit to be gained
from routine estradiol measurement as part of investigating men who complain about infertility. Low
testosterone does not cause stomach discomfort. In fact, sperm production is stimulated by hormones other
than testosterone.

Author Biography

  • Archana Dhok1 , Ranjit Sidram Ambad2 , Sanjay Deshpande3 , Ninad Nagrale4

    1
    Professor and HOD, Dept. of Biochemistry Jawaharlal Nehru Medical College and Datta Meghe Institute of
    Medical Science Sawangi (Meghe) Wardha-442001 Maharashtra; India, 2
    Associate Professor Department of
    Biochemistry, Datta Meghe Medical College, Shalinitai Meghe Hospital and Research Centre, Nagpur-441110,
    Maharashtra; India, 3Professor and HOD, Dept. of Community Medicine Datta Meghe Medical College, Shalinitai
    Meghe Hospital and Research Centre, Nagpur-441110, Maharashtra; India, 4Associate Professor Dept. of Forensic
    Medicine Datta Meghe Medical College, Shalinitai Meghe Hospital and Research Centre, Nagpur-441110,
    Maharashtra; India

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Published

2020-10-29

How to Cite

Role of Oestrogen and Testosterone in Male Infertility. (2020). Indian Journal of Forensic Medicine & Toxicology, 14(4), 6386-6390. https://doi.org/10.37506/ijfmt.v14i4.12603