Case Report on Marfans Syndrome

Abstract

Marfan syndrome (MFS) is one of the most common inherited disorders of connective tissue. It is an
autosomal dominant condition with a reported incidence of 1 in 3000 to 5000 individuals. There is a wide
range of clinical severity associated with MFS with classic ocular, cardiovascular and musculoskeletal
abnormalities, while some patients demonstrate significant involvement of the lung, skin and central nervous
system. A 11 years old female child came to the ophthalmology OPD with chief complaints of diminution of
vision in both eyes, more in right eye since last 2 months. Patient also complains of pain in right eye since
last 3 days. On examination patient had a tall stature, arachnodactyly with positive wrist and thumb signs,
right eye had superotemporal subluxation of lens,the left eye had temporal subluxation with iridodonesis on
autorefractometer patient was having high myopic reading