Case Report-Primary Renal Lymphoma: A Rare Entity

Abstract

Background: Kidney involvement is an under-recognized complication of both Hodgkin and non-Hodgkin
lymphoma (NHL).1,2 Many patient presents with acute kidney injury in newly diagnosed NHL, but patient
being diagnosed with primary renal NHL is very rare. As it rarely occurs, it may not be considered initially
during patient presentation. In patient presenting with idiopathic kidney failure along with non-specific pain
in abdomen, primary NHL must be kept in mind. Below we present a patient who presented with pain in
abdomen and was later diagnosed as a rare case of primary renal NHL.
Case History: A 65 year old male presented with the chief complaints of pain in abdomen since 2 months
and history of nocturia 3-4 times at night and dribbling of urine since 1 month. There were no significant
findings on general and systemic examination. CT scan revealed a solitary renal mass of 90 × 85 × 61 mm
in upper pole of left kidney. Patient underwent Radical Nephrectomy and on histopathology specimen was
diagnosed as - Infiltration of Non-Hodgkins lymphoma in kidney. Primary renal NHL.
Conclusion: Primary involvement of kidney in NHL is extremely rare entity which should be always kept
as differential diagnosis in case of radiological suspicion of primary renal mass. NHL is diagnosed on
histopathological grounds and can be first proven by performing renal biopsies in order to start chemotherapy
which is the main modality in treatment of PRL. Recent immunohistochemical tests allow correct diagnosis
and also helps in classifying renal lymphomas.