Gastrointestinal Stromal Tumourmetastasis in Lymph Node: A Case Report

Abstract

Background: GIST are the tumours originating in the gastrointestinal tract with a high malignant potential
and the chance to metastasize and recur. They are widely studied due to their distinctive biologic behavior,
clinicopathological manifestations, molecular mechanisms and treatment modalities. They can affect any
part of gastrointestinal tract or extraintestinal sites. Most GISTs stain positive for KIT, CD117 andanoctamin1(DOG-1). Tumorresection along with Imatinib therapy is said to be mainstay of the treatment.
Case Presentation: Here by presenting a case of a male aged 60 years operated for cholecystectomy and
intraoperatively found to have a solitary nodule over the stomach, which was later found out to be GIST
metastasis to a lymph node on histopathology.
Conclusion: GIST has a low incidence and rare tendency to metastasize to lymph node; therefore it is
important to study clinical importance to lymph node in this malignancy. Lymph node dissection should
therefore be kept in mind during resection of GIST.