Signet Ring Cell Carcinoma

Abstract

Signet ring cell carcinoma is very rare carcinoma of colon and aggressive subtype of colorectal carcinoma that
is mostly diagnose inadvance stage. 5-year survival rate is very poor as compared to other adenocarcinoma
of the colon. First case reported in 1951 but clinical literature on this subtype of adenocarcinoma is very
limited. In this report a 32-year old male presented with SRCC of colon. Our literature review describes
the many factors that contribute to the poor outcome and high recurrence in SRCC of the colon. This study
prove that survival rate is increased by earlydiagnosis and surgical resection. However, the rarity of this
cancer and its propensity for insidious onset and aggressive course prove a challenge to the development of
such guidelines.