Homocysteinemia: Cause of a Rare Case Coexisting DVT and Recurrent Foetal Loss in Pregnancy

Abstract

Deep vein thrombosis and venous thromboembolism is a major health problem and one of the leading causes
of maternal morbidity and mortality Recurrent pregnancy loss either early or late is a serious problem and
has both psychological and physical impact. Thrombophilia are one of the most important causes of DVT
as well as Recurrent pregnancy loss as it worsens the physiological hypercoagulable case which exists in
pregnancy. Homocysteinemia is rare but an important cause of deep vein thrombosis and recurrent pregnancy
loss. Serum homocysteine levels in pregnancy have been linked to preeclampsia,recurrent abortions and low
birth weight. Diagnosis of this condition is missed on routine basis due to extremely less frequency of the
evaluation of serum homocysteine levels on a routine basis. Here we report a case of hyperhomocysteinemia
as underlying cause of bad obstetric history and DVT which are few of the classic presentations of the entity
seen in the single patient. the condition was diagnosed by multidisciplinary approach.