Case Report on Thalassemia in Children

Abstract

Introduction: Thalassemia which is also called as Cooley’s anemia or Mediterranean anemia is a group
of hereditary hemolytic anemia characterized by reduction in the synthesis of hemoglobin. The word
‘thalassemia’ is derived from the Greek word ‘Thalassa’ which means the great sea.
Clinical Findings: Abdominal pain, fever (Temperature - 101°F), Anemia (Hb – 6.4gm%).
Diagnostic Evaluation: Blood test: Hb – 6.4gm%, Total RBC count – 2.3 millions/cu mm, RDW – 18.2%,
HCT – 20.2%, Total WBC count – 3200/cu mm, Monocytes – 02%, Granulocytes – 20%, Lymphocytes –
77%, AST(SGOT) – 112 U/L.
Peripheral Smear: RBC – mild hypochromic with mild cytosis which show few microcytic and mildly
hypochromic. Platelets – Reduced on smear, APC – 62,000 cells.
Ultrasonography: Splenomegaly.
Therapeutic Intervention: Blood transfusion, Inj. Cefotaxime 750mg IV x BD, Syr. Azee 4ml x OD, Tab.
Folic Acid 5mg x OD, Tab. Udiliv 150mg x BD, Cap. Hydra 500mg x OD, Tab. Prednisolone 10mg x BD.
Outcome: After treatment, the child show improvement. His fever and abdominal pain were relieved and
his Hb% increased from 6.4gm% to 11gm% after blood transfusion.
Conclusion: My patient was admitted to Pediatric Ward No – 14, AVBRH with a known case of Thalassemia
and he had complaint of fever and abdominal pain. After getting appropriate treatment his condition was
improved.