Prevalence of Different Resistance Pattern in Staphylococcal Aureus Isolates From Tertiary Care Hospital

Authors

  • Dhruba Hari Chandi1 , Dr. Nandkishor Bankar2 , Ranjit Ambad3 , Brij Raj Singh4 , Karan Jain5

DOI:

https://doi.org/10.37506/ijfmt.v14i4.12711

Keywords:

Inducible Clindamycin Resistance (ICR), Staphylococcus aureus, MRSA, MSSA, D-test

Abstract

Introduction: Staphylococcus aureus is common isolated pathogen from clinical specimen with increasing
trend of antimicrobial resistance. Staphylococcus aureus and Coagulase-negative Staphylococci (CoNS)
infections have become common among both hospitalized and non-hospitalized patients.
Aim: The aim of this study was to determine the inducible clindamycin resistance among the MRSA and
MSSA.
Material and Method: This study was prospective study which includes the entire sample obtained in the
Department of Microbiology laboratory from Tertiary Care Hospital with bacterial infection and confirmed
by positive culture. The standard microbiological protocol for detection of inducible clindamycin, Disc
approximation method (D–test) was performed.
Result: Out of 124 Staphylococcus aureus isolates, 17 (13.7%) were inducible clindamycin resistant; 6
(35.29%) from (cefoxitin susceptible) MSSA and 11 (64.71%) from (cefoxitin resistance) MRSA.
Conclusion: The incidence of inducible clindamycin resistance among the Staphylococcus aureus was high.
This high rate screen among the MRSA and MSSA provokes the necessity of performing the D- test before
starting the antibiotic therapy.

Author Biography

  • Dhruba Hari Chandi1 , Dr. Nandkishor Bankar2 , Ranjit Ambad3 , Brij Raj Singh4 , Karan Jain5

    1
    Assistant Professor, Department of Microbiology, Jawaharlal Nehru Medical College, Sawangi (M), Wardha,
    Maharashtra, 2Assistant Professor, Department of Microbiology, Datta Meghe Medical College, Wanadongri,
    Hingna Road, Nagpur, Maharashtra, 3Associate Professor, Department of Biochemistry, Datta Meghe Medical
    College, Wanadongri, Hingna Road, Nagpur, Maharashtra, 4
    Professor, Department of Anatomy, Datta Meghe
    Medical College, Wanadongri, Hingna Road, Nagpur, Maharashtra, 5Statistician, Department of Microbiology,
    Datta Meghe Medical College, Wanadongri, Hingna Road, Nagpur, Maharashtra, India

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Published

2020-10-29

How to Cite

Prevalence of Different Resistance Pattern in Staphylococcal Aureus Isolates From Tertiary Care Hospital. (2020). Indian Journal of Forensic Medicine & Toxicology, 14(4), 6908-6912. https://doi.org/10.37506/ijfmt.v14i4.12711