Supplementation of Vitamin D in Diabetic Patients

Abstract

Background: Nearly 30 percent to 50 percent of people are estimated to have deficiency of vitamin D,
and insufficiency and vitamin D deficiency are recognized as global health issues in the world. Although
the presence of hypo-vitamin D raises the risk of rickets and fractures, higher levels of vitamin D are also
associated with hypertension (HTN), cardiovascular disease (CVD) and cancer. In addition, the vitamin
D levels are also associated with diabetes mellitus (DM) and chronic kidney disease (CKD). Deficiency
of vitamin D was linked to DM induction and progression. While the relationship between vitamin D and
insulin secretion, insulin tolerance, and ?-cell dysfunction is highlighted in patients with DM, evidence of
vitamin D and DM levels is inconsistent, and well-controlled studies are required.
Aim: Supplementation of vitamin D in diabetic patients.
Material and Method: The study included 50 patients were given vita D supplement and 50 subjects were
not given vita D supplement in diabetic people as the control group. Directly Observed Treatment in the
Department of Clinical Biochemistry, Datta Meghe Medical College, SMHRC, Nagpur in collaboration with
JNMC, ABVRH (Datta Meghe Institute of Medical Sciences Deemed To Be University), Sawangi, Wardha,
Maharashtra.
Conclusion: This study evaluated that vitamin D supplementation can improve HbA1c, insulin resistance,
and insulin in short-term intervention in T1DM & T2DM patients, suggesting that vitamin D can be
considered as a therapeutic agent along with the other T1DM & T2DM treatments. The findings show that
in non-additional diabetic patients, vit D concentration was substantially lower than the additional diabetic
individuals.