Rasaushadhi (Herbomineral Formulations) Induced Nephrotoxicity in Children: Safety Concern Case Series

Authors

  • Rekha V Shinde1 , Ranjit Ambad2 , Pradip Adhav,3 Praful Fadanvis4 , Swarupa Chakole5

DOI:

https://doi.org/10.37506/ijfmt.v14i4.12741

Keywords:

Nephrotoxicity, Rasaushadhi, Herbomineral medicines, Kidney injury, Ayurvedic drug’s safety, Paediatric nephrotoxicity, Kidney Function Test.

Abstract

Background: Use of Rasaushadhi (Herbomineral formulations) in children is sensible topic. In last decade,
some articles reported in various newspapers about nephrotoxicity of Ayurvedicherbomineral medicines.
These issues create negative impression regarding the use of Ayurvedicherbomineral medicines. Ayurveda
itself a time tested life science and provide guidelines to stay healthy and preserve the health. Such articles
have done considerable damage to the reputation of ayurveda but at same time, it has raised many questions
which need to be addressed. To make system more scientific and evidence based study was conducted at
Paediatric department of Government institute in 2017. Paediatric department in this institute has used
Rasaushadhi in children several times and not noted any problem regarding nephrotoxicity till date.
Aim: Question: Does Rasaushadhi (Herbomineral formulations) cause Nephrotoxicity in children? To
determine Rasaushadhi (Herbomineral formulations) is “safe” study was conducted.
Materials and Method: Study was conducted for recurrent and reactive respiratory illness in children and
herbomineral five drugs regimen was given to children of age 4 to 14 years for 45 days at 15 days interval.
To rule out Nephrotoxicity after the use of Ayurvedicherbomineral formulations kidney function test was
done. Patients were clinically observed in 4 follow ups, each follow up was conducted every 15 days. Last
(Fourth) telephonic follow up was taken after six months of completion of treatment course to observe any
renal obstructive pathology.
Results: Total 13 patients of case series were observed normal kidney function test reports. Last (Fourth)
telephonic follow up was also reported normal, no any renal complications reported.
Conclusion: This clinical case series found that use of Ayurvedicherbomineral medicines in paediatric
patients is safe and there is no relation with nephrotoxicity or any obstructive renal pathology when used
properly

Author Biography

  • Rekha V Shinde1 , Ranjit Ambad2 , Pradip Adhav,3 Praful Fadanvis4 , Swarupa Chakole5

    1
    Assistant Professor, Dept. of Kaumarbhritya, Datta Meghe Ayurvedic Medical College, Hospital and Research
    Centre, Nagpur 440034, 2Associate Professor, Dept. of Biochemistry, Datta Meghe Medical College, Shalinitai
    Meghe Medical College and Hospital, Nagpur, 3
    Associate Professor, Dept. of Surgery, Bhausaheb Mulak Ayurvedic
    College, Butibori, Nagpur, 4
    Associate Professor, Dept. of Shalyatantra, Datta Meghe Ayurvedic Medical College,
    Hospital and Research Centre, Nagpur, 5Professor Dept. of Community Medicine Jawaharlal Nehru Medical
    College, Datta Meghe Institute of Medical Sciences, Sawangi (Meghe), Wardha

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Published

2020-10-29

How to Cite

Rasaushadhi (Herbomineral Formulations) Induced Nephrotoxicity in Children: Safety Concern Case Series. (2020). Indian Journal of Forensic Medicine & Toxicology, 14(4), 7018-7022. https://doi.org/10.37506/ijfmt.v14i4.12741