Disturbance of Coagulative Hemostasis among Patients with Henoch-Schonlein Purpura

Abstract

The Purpose: To examine the state of thrombocytic and coagulation hemostasis among patients with
immune microthrombovasculitis.
Materials and Method: The study included 75 patients with immune microthrombovasculitis. Among
them, rmen - 24 (32%), women - 51 (68%), the average age is 42.4±1.3 years. The control group consisted
of 15 practically healthy persons.
Results and Discussion: A study of coagulation hemostasis among patients with immune
microthrombovasculitis showed the presence of hypercoagulation shift with the increase of fibrinogen
concentration, prothrombin index, shortening of the active partial thromboplastin time and blood clotting
time, the appearance of hybrid monolith complexes - level increase of D-dimer positive ethanol test.
Conclusions: The most common clinical form of IMTV is the skin-joint form of the disease (62.2%),
89.3% of patients were admitted with an acute form of the disease. Women get sick twice as often (67.3%)
than men (32.7%), the highest incidence is in the young age group from 18 to 49 years (87.3%). There is
hypercoagulability in case of immune microthrombovasculitis.