The Study of Antiallergic Activity of the Phytocollection of “Phytoallergoderm”

Abstract

The antiallergic activity of “Phytoallergoderm” phytocollection was studied, which was recommended for
topical treatment of a topic dermatitis, on the model of allergic contact dermatitis, caused by skin application
of turpentine. The following drugs were used as comparison: antihistamine “Psilo-Balsam” gel, manufacturer:
OJSC “Nizhpharm” Russia; glucocorticoid (topical steroid) “Dermoveit” cream 0.05%, manufacturer:
“Glaxo Smith Kline Pharmaceuticals SA” Poland; zinc product “Zinc” ointment, manufacturer: NPP
“Radiks” Uzbekistan.
During the experiment, it was found that the test drug has a reliable anti-allergic activity, which is clearly
caused of decrease in total allergic reactions, in the reduction of recovery time and in a decrease in the
dynamics of the severity of allergic reactions. Also, the study of antiallergic activity showed that the test
drug has a comparable antiallergic activity with the etalon synthetic drug.
The foregoing indicates the presence of a reliable anti-allergic activity of the phytocollection
“Phytoallergoderm”, which is comparable to reference synthetic preparations.