Pemphigus Vulgaris: Oral Pathologist as Sentinal

Abstract

The word ‘Pemphigus’ has been derived from a Greek term meaning “blister”. Pemphigus vulgaris is a chronic
autoimmune vesiculobullous lesion primarily manifesting as intraoral blisters, gradually involving other
parts of the mucous membrane and skin. Though the exact etiology is unknown the lesion is characterized
by the production of autoantibodies directed against the intercellular substances thus categorizing it as an
autoimmune disorder. Early diagnosis and management determine the course of the lesion hence dental
practitioners should be well aware of the clinical features of pemphigus vulgaris as early diagnosis is of
considerable value since therapy is simplified when the lesion is confined to the mouth. Here we are reporting
a case of a 40 year old female presenting with pain and burning sensation in the left retromolar area along
with an overview of the disease.