Platelet-Rich Fibrin: An Update

Abstract

The development of bioactive surgical additives to regulate the inflammation and increase the speed of
the healing process is one of the great challenges in clinical research. In this sense, platelet-rich fibrin
(PRF) appears as a natural and satisfactory alternative with favorable results and low risks. The following
review attempts to summarize the relevant literature regarding the technique of using PRF, focusing on its
preparation, advantages, and disadvantages of using it in clinical applications and its updates. PRF alone or
in combination with other biomaterials seems to have several advantages and indications both for medicine
and dentistry, due it is a minimally invasive technique with low risks and satisfactory clinical results