Comparative Study of Magnesium Sulphate added to Bupivacaine and Ropivacaine Local Infiltration of Wound for Postoperative Analgesia in Patients Undergoing Upper Abdominal Surgery: A Randomized Double Blind Study

Authors

  • Anuja Agrawal
  • Sujay Thakkar
  • Akhilesh Chhaya
  • Malini Mehta

DOI:

https://doi.org/10.37506/ijfmt.v15i2.14277

Keywords:

Local Infiltration, Ropivacaine, Bupivacaine, Magnesium Sulphate, Postoperative pain

Abstract

Aim: To compare subcutaneous infiltration of Inj Bupivacaine with inj MgSO4and Inj Ropivacaine with
InjMgSO4 for postoperative analgesia undergoing upper abdominal surgery. Goal: To determine duration of
analgesia, doses of rescue analgesia, VAS at different time intervals.
Background: Post-operative pain is most neglected entity. We should use availableresources in
optimummanner for improving pain managementstrategies.
Methods: A Prospective, double-blinded, randomized studyof 50 patients undergoing upper abdominal
surgery divided into group B and R. Infiltration was done in the subcutaneous plane by surgeon before skin
closure. Group B: Inj. Bupivacaine 50mg (10ml of 0.5% Inj . Bupivacaine) with Inj.MgSO4 500mg (1ml of
Inj 50% MgSO4) diluted with NS 9 ml to make total volume of 20 ml whereas, Group R: Inj Ropivacaine
50 mg (6.7 ml of 0.75% Inj. Ropivacaine) with Inj MgSO4 500 mg diluted with NS (12.3 ml) making a total
volume of 20 ml. In postoperative period, parameters noted were vitals and Visual Analogue Score (VAS)
for 24 hours.
Results: In group R, moderate pain was seen in 40%of the patients at T12 whereas in group B 48% had
moderate pain. Total no. of rescue analgesic doses required in Group R is 2.1 +/- 0.5 and in Group B is 2.6
+/- 0.5 in 24 hrs and has significant differencestatistically.
Conclusion: Group R had better VAS scores at T24 and reduced no.of rescue analgesic doses.

Author Biographies

Anuja Agrawal

Associate Professor

Sujay Thakkar

Assistant Professor, Department of Anaesthesiology, Dhiraj Hospital, Smt. B.K.Shah Medical
Institute & Research Centre Sumandeep Vidyapeeth Deemed To Be University,Vadodara, Gujarat

Akhilesh Chhaya

Professor,
Department of Anaesthesiology, Gujarat Adani Institute of Medical Sciences, Bhuj,Gujarat

Malini Mehta

Professor, Department
of Anaesthesiology, Dhiraj Hospital, Smt. B.K.Shah Medical Institute & Research Centre Sumandeep Vidyapeeth
Deemed To Be University, Vadodara, Gujarat

Published

2021-03-24

How to Cite

Anuja Agrawal, Sujay Thakkar, Akhilesh Chhaya, & Malini Mehta. (2021). Comparative Study of Magnesium Sulphate added to Bupivacaine and Ropivacaine Local Infiltration of Wound for Postoperative Analgesia in Patients Undergoing Upper Abdominal Surgery: A Randomized Double Blind Study. Indian Journal of Forensic Medicine & Toxicology, 15(2), 78-84. https://doi.org/10.37506/ijfmt.v15i2.14277