Utility of the Cell Block Preparation as an Additive Tool to the Conventional Cytological Smears
Keywords:Conventional smear, Cell block, body (effusion) fluids, Fluid Cytology.
Background: For the detection of malignancy in the serous fluids of the body, cytological examination of
the fluid is very important. It is also of prime importance and seems difficult to differentiate the malignant
cells from reactive mesothelial cells during fluid cytology. The cell block preparation is a useful and additive
diagnostic tool when cellular features in cytology are inconclusive or suspicious. The aim of the study was
to assess the utilization of the cell technique as an additional tool along with the conventional smears that
we are using in routine practice.
Methods: 200 body (effusion) fluids were examined by the conventional cytological smears as well as by
the cell block technique.
Conclusion: The diagnostic yield increases when we use the cell block preparation method along with the
conventional smears because the architectural patterns and cell morphology are very well preserved in cell
block as compared to the smears.
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