Bacteriological Profile of Health Care Associated Infection and Antibiotic Resistance Pattern of Isolates at Picu in a Tertiary Care Hospital
Keywords:VAP- ventilator associated pneumonia, CRBSI- catheter related blood stream infection, CAUTI - catheter associated urinary tract infection, PICU - Pediatric intensive care units
Background: Healthcare Associated Infections (HAIs) are a major cause of morbidity and mortality in
Pediatric intensive care units (PICUs). The aim was to determine bacteriological profile of HAI and to
establish an antibiogram of isolates in our PICU.
Materials and Method: This was a retrospective study conducted at the Department of Pediatrics (Pediatric
Intensive Care Unit) of AIIMS, Jodhpur. Data was collected over 2 years from January 2017 to December
2018. Among the114 culture positive isolates, 50% (57/114) were gram negative and 22.8% (26/114) were
gram positive organisms. Culture positivity for fungal growth was 14 % (17/114) and rest 12.2% (14/114)
were contaminants. The most common isolate in gram negative organism was Acinetobacter baumannii and
in gram positive organism most common isolates were Enterococcus. Most commonly detected HAI types
were ventilator associated pneumonia (VAP) - 34% (20/59). All gram negative organisms were resistant to
carbepenems except Pseudomonas (100% sensitivity). Among gram positive organisms, methicillin resistant
staphylococcus aureus (MRSA) was 100% sensitive to gentamicin, amikacin, vancomycin and linezolid.
Conclusion: The retrospective study showed that both gram positive and negative bacteria as well as fungal
organisms are responsible for HAIs. Most of the strains were multi drug resistant.
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