Evaluation of Ehretia Laevis Roxb. (Khandu Chakka/Ajan Vruksha) in the Wound Healing Adjudged by Histological Examination of the Tissue

Abstract

Many herbal plants are mentioned in Ayurveda for wound healing. Folklore medicine for various ailments
including wound healing is being practiced in India. Ehretia Laevis Roxb. contains many such chemical
compounds useful for promotion of healing & repair. Tissue renewal goes hand in hand with inflammation
influenced by multiple processes. Ehretia Laevis Roxb. called Khandu Chakka & Ajan Vruksha and
traditionally being used for wound healing, body pain & minor fractures in the form of local application by
folklore in the state of Maharashtra India. Objectives of the present study is to know the effect of Ehretia
Laevis Roxb. in the wound healing on the histological parameters in animal model. Phenytoin ointment
as a control was used. The present study has found put that leaf extract paste of Ehretia Laevis Roxb.
has enhanced the process of wound healing ascertained on histological parameters as compared to topical
phenytoin application. Ehretia Laevis Roxb. paste is found to be immensely useful at wound healing as
compared to Phenytoin. Ehretia Laevis Roxb. is concluded to promote the healing significantly as observed
by feature of granulation, collagenisation & re epithelisation of the wounds suggesting early healing by
primary intension