Evaluation of Ehretia Laevis Roxb. (Khandu Chakka/Ajan Vruksha) in the Wound Healing Adjudged by Histological Examination of the Tissue

Authors

  • Rushikesh Thakre
  • Arvinda Bhake
  • Pradip Tekade
  • Ketaki Harne
  • Preeti Sujit Borkar

DOI:

https://doi.org/10.37506/ijfmt.v15i2.14397

Keywords:

Ehretia Laevis Roxb., Phenytoin, Khandu Chakka, Ajan Vruksha, Wound healing , Histological study.

Abstract

Many herbal plants are mentioned in Ayurveda for wound healing. Folklore medicine for various ailments
including wound healing is being practiced in India. Ehretia Laevis Roxb. contains many such chemical
compounds useful for promotion of healing & repair. Tissue renewal goes hand in hand with inflammation
influenced by multiple processes. Ehretia Laevis Roxb. called Khandu Chakka & Ajan Vruksha and
traditionally being used for wound healing, body pain & minor fractures in the form of local application by
folklore in the state of Maharashtra India. Objectives of the present study is to know the effect of Ehretia
Laevis Roxb. in the wound healing on the histological parameters in animal model. Phenytoin ointment
as a control was used. The present study has found put that leaf extract paste of Ehretia Laevis Roxb.
has enhanced the process of wound healing ascertained on histological parameters as compared to topical
phenytoin application. Ehretia Laevis Roxb. paste is found to be immensely useful at wound healing as
compared to Phenytoin. Ehretia Laevis Roxb. is concluded to promote the healing significantly as observed
by feature of granulation, collagenisation & re epithelisation of the wounds suggesting early healing by
primary intension

Author Biographies

Rushikesh Thakre

Assistant Professor , Department of Samhita Siddhant, MGACH & RC, Datta Meghe Institute Medical Sciences
( DU) Wardha( MS) India

Arvinda Bhake

Professor Department of Pathology,JNMC, Datta Meghe Institute Medical Sciences
( DU) , Wardha( MS), India

Pradip Tekade

Associate Professor Department of Chemistry Bajaj College of Science(Formerly
known as Jankidevi Bajaj College of Science), Wardha (MS), India

Ketaki Harne

PhD scholar( Chemistry), Rastra Santa
Tukadoji Maharaj Nagpur University Nagpur ( MS). India

Preeti Sujit Borkar

Professor & Head, Department of Samhita& Siddhant
MGACH & RC, Datta Meghe Institute Medical Sciences ( DU) Wardha( MS) India

Published

2021-03-24

How to Cite

Rushikesh Thakre, Arvinda Bhake, Pradip Tekade, Ketaki Harne, & Preeti Sujit Borkar. (2021). Evaluation of Ehretia Laevis Roxb. (Khandu Chakka/Ajan Vruksha) in the Wound Healing Adjudged by Histological Examination of the Tissue. Indian Journal of Forensic Medicine & Toxicology, 15(2), 713-721. https://doi.org/10.37506/ijfmt.v15i2.14397

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