The Clinical Effect of Super Oxidized Water Mouthwash on The Periodontal Parameters (Plaque Index, Gingival Index And Bleeding on Probing) for Patients with Dental Biofilm Induced Gingivitis
Keywords:super oxidized water, chlorhexidine, distilled water, plaque index, gingival index, bleeding on probing, Microsafe®, Kin gingival®.
Background: One of the most predominant periodontal diseases is the dental biofilm induced gingivitis. : For
the past 20 years, super-oxidized solutions have been shown to be powerful antimicrobials and disinfectants
via oxidative damage. The taste is better than chlorhexidine and doesn’t stain the teeth. Microsafe®, a superoxidized solution for gingival care, offers a completely improved approach to treatment of gingivitis.
Aim: To evaluate the efficacy of super oxidized water mouthwash by improving gingival health in dental
biofilm induced gingivitis. .
Materials and Methods: 45 adult male patients with generalized dental biofilm induced gingivitis
participated in the double blinded randomized controlled parallel study divided into three groups, two
mouthwashes and distilled water( negative control) used during seven days periods as adjunctive to regular
mechanical oral hygiene(brushing and interdental aids cleaning), one group received super oxidized water
mouthwash (Microsafe®) three times daily and the second group received 0.12% alcohol-free chlorhexidine
mouthwash (Kin gingival®) twice daily and the third group received distilled water twice daily (negative
Results: According to the plaque index, highly significant improvement of all treatment groups was observed
in the second visit one-week post treatment. Microsafe® (SOW) showed to have clinical outcomes closed
to the effect of CHX (the positive control) than the negative control group (D.W group). According to the
GI, there was a significant difference between the study groups in the2nd visit after treatment and CHX was
appeared to be most effective when compared to Microsafe®.
According to BOP , all the treatment groups showed reduced BOP one-week between the 1st visit and the 2nd
visit ; although, CHX showed better outcomes (the mean difference was 14.258 ) when compared to D.W
and Microsafe® groups( the mean differences were 10.838, 9.9 respectively).
Conclusion: There was a positive effect of topical application of Microsafe® mouthwash as adjunctive
to regular mechanical oral hygiene on gingival inflammation three times daily after one week. This was
improved by clinical periodontal parameters (PlI , GI and BOP).
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