Synthesis and Identification and Biological Studies of New Azo Dyes Derived from Imidazole and their Chelate Complexes

Authors

  • Fatima J. Ali
  • Layla A. M. AL-Ameri
  • AbidAllah M. Ali

DOI:

https://doi.org/10.37506/ijfmt.v15i2.14496

Keywords:

Synthesis, Biological activity, Lung Cancer.

Abstract

Anew azo ligand (E)-2-((4- fluoro phenyl)diazenyl)-4,5-bis(4-methoxy phenyl)-1H-imidazolehas been
synthesized from coupling 4,5-bis(4-methoxyphenyl)imidazole with para-chloro-anline. The structures of
the new ligand and their transition metal complexes ware investigated and characterized using different
physicochemical studies as elemental analysis, IR spectra, 1
HNMR,, UV-Vis spectra, mass spectra, Molar
conductance ,and magnetic susceptibility .The complexes were found to have the general formula [ML2Cl2].
H2O where M = Co(II), Ni(II), Cu(II) ,Mn(II),and Fe(II), [MLCl2].H2Owhere M=Zn(II),Cd(II),Hg(II), and
Pd(II). The IR results demonstrate that the co-ordination sites are the azomethine nitrogen of the imidazole
ring and azo nitrogen atom of the azo ligand. The electronic spectral and magnetic measurement data
indicate that the complexes exhibit octahedral geometry,except the Zn(II),Cd(II),andHg(II) complexes
suggest tetrahedral and Pd(II) a square planar geometry.The cytotoxicity of Pd(II) complex on human Lung
Cancer (SCLC) and normal cells.

Author Biographies

Fatima J. Ali

Post graduate

Layla A. M. AL-Ameri

Prof. Dr. Department of Chemistry, College of Education for Women, University of Kufa,
Najaf-Iraq

AbidAllah M. Ali

Prof. Dr. Department of Chemistry, College of Education for Women, University of Kufa,
Najaf-Iraq

Published

2021-03-24

How to Cite

Fatima J. Ali, Layla A. M. AL-Ameri, & AbidAllah M. Ali. (2021). Synthesis and Identification and Biological Studies of New Azo Dyes Derived from Imidazole and their Chelate Complexes. Indian Journal of Forensic Medicine & Toxicology, 15(2), 1253-1260. https://doi.org/10.37506/ijfmt.v15i2.14496