Synthesis and Identification and Biological Studies of New Azo Dyes Derived from Imidazole and their Chelate Complexes
Keywords:Synthesis, Biological activity, Lung Cancer.
Anew azo ligand (E)-2-((4- fluoro phenyl)diazenyl)-4,5-bis(4-methoxy phenyl)-1H-imidazolehas been
synthesized from coupling 4,5-bis(4-methoxyphenyl)imidazole with para-chloro-anline. The structures of
the new ligand and their transition metal complexes ware investigated and characterized using different
physicochemical studies as elemental analysis, IR spectra, 1
HNMR,, UV-Vis spectra, mass spectra, Molar
conductance ,and magnetic susceptibility .The complexes were found to have the general formula [ML2Cl2].
H2O where M = Co(II), Ni(II), Cu(II) ,Mn(II),and Fe(II), [MLCl2].H2Owhere M=Zn(II),Cd(II),Hg(II), and
Pd(II). The IR results demonstrate that the co-ordination sites are the azomethine nitrogen of the imidazole
ring and azo nitrogen atom of the azo ligand. The electronic spectral and magnetic measurement data
indicate that the complexes exhibit octahedral geometry,except the Zn(II),Cd(II),andHg(II) complexes
suggest tetrahedral and Pd(II) a square planar geometry.The cytotoxicity of Pd(II) complex on human Lung
Cancer (SCLC) and normal cells.
How to Cite
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Re use and mixing of content policy- We follow Creative Commons Licence Policy. We follow CC BY. Please refer below for all details
This license lets others distribute, remix, adapt, and build upon our work, even commercially, as long as they credit us for the original creation.
- The journal allows readers to read, download, copy, distribute, print, search, or link to the full texts of its articles and allow readers to use them for any other lawful purpose.
- The journal allows the author(s) to hold the copyright without restrictions.
- The journal allows the author(s) to retain publishing rights without restrictions