Detection Levels of Cytokines (IL-6 and IL-18) and Microbial Parameters in Patients with Renal Failure in Diyala Province

Authors

  • Wasan A. Wahab Alsiadi
  • Alaa Mohammed Albayati
  • Ban Talib Elhaboby

DOI:

https://doi.org/10.37506/ijfmt.v15i2.14546

Keywords:

Renal failure, , microbial infection, and (IL-6 and IL-18)

Abstract

Current study was conducted in Diyala province for kidney failure patients ( Ibn Sina Center ) for dialysis
in Baqubah teaching hospital and started from beginning August 2016 to end April 2017. A total 100 blood
sample had from kidney failure patients, has been the number males 61 and females 39 with age range (10
– 88) years and collected 50 of blood sample from oculary healthy individuals act as a control group , has
been the number males 25 and females 25 with age range 10 – 88 years . By (ELISA) technique detection
immunological parameters (IL-6 , IL-18) , and (SRID) for detection microbial parameters (HBV, CMV , T.
gondii, HCV) . Result of study expressed that the incidence of disease rate among males 61% more than
females 39% with no significant different (P>0.05), also highest rate disease in both age groups (31-50, 51-
70) years , while lowest rate disease the age range (10-30 , >70) years recorded with significance different)
P <0.05(. So, high levels of ( IL-18) for patients than to control with significance different between study
groups (P <0.05), while (IL-6) was raised in patients compared to control. Also, result showed positivity of
( HBV, CMV , T. gondii, HCV ) in patients was (8% , 13%, 10%, 25% ) respectively with high significant
different (P<0.05). Conclusions of current study showed male more than female, age period >70 and 51-17
year recorded highest percentage infection ,high levels of immunological (IL-6 and IL-18) in renal dialysis
patients, as well as to some microbial infected patients with kidney failure. The aim of study is detection
levels of cytokines (IL-6 and IL-18) and some microbial infection in patients with renal failure.

Author Biographies

Wasan A. Wahab Alsiadi

Doctor, Bilad AlRafidain University College, Dept. of Medical Labs. Techniques

Alaa Mohammed Albayati

Assistant Lecturer, Bilad
Al-Rafidain University College, Dept. of Medical Labs. Techniques

Ban Talib Elhaboby

Lecturer, Biology Department, College of
Science, Mustansiriya University. Iraq

Published

2021-03-24

How to Cite

Wasan A. Wahab Alsiadi, Alaa Mohammed Albayati, & Ban Talib Elhaboby. (2021). Detection Levels of Cytokines (IL-6 and IL-18) and Microbial Parameters in Patients with Renal Failure in Diyala Province. Indian Journal of Forensic Medicine & Toxicology, 15(2), 1470-1475. https://doi.org/10.37506/ijfmt.v15i2.14546