Evaluation of Lipocalin-2 and Visfatin, and Vitamin (D,C, and E) in Serum of Diabetic Patients with Chronic Periodontitis
DOI:
https://doi.org/10.37506/ijfmt.v15i2.14578Keywords:
Type2 diabetes; Visfatin; Lipocalin-2;Serum.Abstract
Objective: The aim of the present study is to verify the hypothesis that salivary and serum lipocalin-2
and visfatin, and vitamin (D,C, and E) used as indicators for chronic periodontitis among DMT2 patients.
Subjects and methods: We enrolled 41 type 2 diabetic patients with chronic periodontitis -18 males and 23
females, aged 60± 14 years and 49 controls- 26 males and 23 females, aged 61.8 ± 12.5 years. Blood samples
were collected after an overnight fast and routine biochemical parameters such as glucose, lipocalin-2 and
visfatin, and vitamin (D,C, and E)were determined in all samples. Data were considered significant at a level
of p < 0.05.Periodontitis status was established using classic clinical parameters, Plaque index (PI), gingival
index (GI), probing depth (PD) and clinical attachment level (CAL). Results: 1) The mean serum of blood
glucose, Visfatin, and LCN2 were higher in patients group than in those with normal control group (P<0.001
for all comparisons) ; 2) patients with had a lower Vitamin D,C, and E than those with a normal group (P <
0.001 for all comparisons).Conclusions: The activity of lipocalin-2 and visfatin in saliva and serum can be
useful in diagnosis, monitorization and treatment of this disease. Further studies are needed to elucidate the
role of lipocalin-2 and visfatin in periodontitis and systemic disease interactions.
Downloads
Published
Issue
Section
License
- The journal allows readers to read, download, copy, distribute, print, search, or link to the full texts of its articles and allow readers to use them for any other lawful purpose.
- The journal allows the author(s) to hold the copyright without restrictions.
- The journal allows the author(s) to retain publishing rights without restrictions