Evaluation of Mirror Image Biopsy Technique for the Detection of Field Change in Patients with Squamous Cell Carcinoma of the Tongue
Keywords:squamous cell; carcinoma of the tongue, Toxicity; biopsy technique
Background: Oral cancer is one of the most common type of head and neck cancer, with a 5 year survival
rate of < 50%. One of the major problems of oral cancer include the late stage of disease at the time of
diagnosis. Mirror image biopsy is a new technique that can be used for detection of early changes in the
oral mucosa. Aim of the study: To histologically assess the reflect copy biopsy occupied from clinically
usual observing mucosa at consistent contralateral anatomical place to the main lesion in patients identified
with tongue squamous cell carcinoma to notice any indication of arena alteration in oral mucosa. Materials
and methods: Seven patients diagnosed with squamous cell carcinoma of the tongue underwent reflect
copy biopsy from clinically usual observing mucosa at consistent contralateral anatomical place to the main
lesion. The reflect copy biopsy example were exposed to histopathological check. Results: of the seven
patients included, four were male and three were female, with an age range from 45 years to 64 years
(median 54.5 years). One of the biopsies revealed severe dysplasia and six-revealed hyperplasia of the
epithelium. Conclusion: Mirror image biopsy is a useful tool to detect the early field changes in oral mucosa
in order to prevent further progression to oral cancer.
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