Interleukin-8 Concentration Correlation with the Size of Hydatid Cyst in Patients with Hydatidosis and Hepatitis C Mixed Infection (Case Control Study)
Keywords:interleukin-8, hydatidosis, hepatitis C virus, Hydatid cyst.
Background:Hydatid cyst is a disease that is transmitted from the lactating animals that come into contact
with a person, and its danger is to generate hydatid cysts that may put pressure on some vital organs in
the human body. Here comes the role of joint infection with other pathogens such as the hepatitis C virus,
especially in the same organs that are infected with the parasite, which may result from these mixed infections
serious disease complications
Aim of study: The present study aimed to examine the possibility of a relationship between interleukin-8
concentration level with the size of Hydatid cyst patients with mixed infection of hydatidosis and hepatitis
Patients and Methods: The current research was run for the period January 2019 to January 2020. The
patients were referred to AL-Furat al-awsat Hospital , Al-Sadder medical city, Public Health Laboratory
and Al-Hakeem Hospital in Al- Najaf governorate, Iraq. Eighty samples were divided into two groups. This
first group was comprised of 40 patients with hydatidosis, the second group comprised of 40 patients with
hydatidosis and hepatitis c virus mixed infection. The patients were aged 10 to 60 years old.
Result: A higher interleukin-8 concentration was observed in patients with hydatidosis compared to the
healthy group, as the interleukin-8 concentration was (89.36) While the concentration of interleukin- 8
reached in the healthy group (30 .14) ,while A high concentration of interleukin 8 is observed in combined
infection of hydatidosis and hepatitis C virus compaer with healthy group , As the concentration of interleukin
8 in the combined infection of hydatidosis and hepatitis C virus (108.73) while in the healthy group (30.14 ).
Conclusion: The presence of a high level of interleukin-8 in mixed-infection patients is higher than in
single-infection patients, which may lead to exacerbation and complications of hydatidosis disease.
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