Pathological Evaluation of Canine Hepatic Cirrhosis and Necro-inflammatory Activity

Authors

  • Shahad Saad Mahdi
  • Jihad Abdulameer Ahmed

DOI:

https://doi.org/10.37506/ijfmt.v15i2.14606

Keywords:

Pathological, Hepatic, Fibrosis, Canine.

Abstract

Background: Hepatic fibrosis is a common pathological result of chronic liver diseases, which is a dynamic
process of liver decomposition mediated by cellular mediators in response to injury.
Objective: The present study aims to evaluate the histopathological features of dog-liver fibrosis and / or
cirrhosis.
Materials and Methods: 40 liver samples were collected; 12 liver fibrosis suspected animals were performed
the histopathology to determine the main features of canine liver fibrosis.
Results: The histopathology revealed chronic hepatitis with liver islands separated by strips of fibroblasts
and collagen, moderate numbers of macrophages, lymphocytes and plasma cells. Also in fibrosis between
chronic hepatitis/cirrhosis had a wide range of severity and inflammation was observed primarily around
fibrous tissue or was surrounded by fibrous tissue but extended to the liver parenchyma. The histochemical
study revealed to a deposition of collagen fibers in the portal, subscapular and interlobular regions.
Conclusion: The histopathology revealed a range of lesions vary from mild hepatic degenerative changes to
severe fibrotic features associated with canine hepatic fibrosis and early cirrhosis.

Author Biographies

Shahad Saad Mahdi

MSc Student at Pathology and Poultry Diseases Dept., College of Veterinary Medicine, University of Basrah, Iraq

Jihad Abdulameer Ahmed

Pathology and Poultry Diseases Dept., College of Veterinary Medicine, University of Basrah, Iraq

Published

2021-03-24

How to Cite

Shahad Saad Mahdi, & Jihad Abdulameer Ahmed. (2021). Pathological Evaluation of Canine Hepatic Cirrhosis and Necro-inflammatory Activity. Indian Journal of Forensic Medicine & Toxicology, 15(2), 1837-1842. https://doi.org/10.37506/ijfmt.v15i2.14606