The Correlation of Congenital Anomalies of The Kidney and Urinary Tract with Renal Function in Children

Authors

  • Chairunnisa
  • Ninik Asmaningsih Soemyarso
  • Risky Vitria Prasetyo

DOI:

https://doi.org/10.37506/ijfmt.v15i2.14692

Keywords:

Kidney, Urinary tract, Children, CAKUT, GFR

Abstract

Background: Congenital Anomalies Kidney and Urinary Tract (CAKUT) are the leading cause of kidney
failure in children and cause of 30-40% end-stage renal disease with obstructive uropathy as the main cause.
CAKUT obstructive type are: vesico uretric junction obstruction (VUJO), pelvic uretric junction obstruction
(PUJO), posterior uretral valve (PUV) and non-obstructive type are reflux, neurogenic and hypoplasia. The
aim of this study is to describe the effect of CAKUT on renal function in child.
Methods: Retrospective study from medical records of children with CAKUT at Dr. Soetomo General
Hospital, Surabaya, Indonesia from January 2013 - March 2018. The characteristic of sex, age range, type of
CAKUT and glomerulus filtration (GFR) value were recorded from medical record. Data processing using
descriptive analysis with SPSS.
Result: A total of 94 Children on CAKUT abnormalities, both boys and girl’s presentation equal 50%.
Median age 3.0 (minimum-maximum 1.0-15.0) year. The most common CAKUT type in male were VUJO
17 (36.2%) and in female neurogenic type 19 (40.4%). Median initial glomerular filtration rate 2.7 ml/
min/1.73 m2. Analysis of correlation between CAKUT and renal function p=0.072 (R2=0,03). From 94
children of CAKUT, only 12 (12.8%) patients have undergo surgical intervention.
Conclusion: CAKUT with dominant obstructive type was more common in male and non-obstructive type
in female pediatric patient. There was no significance correlation of GFR between obstructive and nonobstructive type.

Author Biographies

Chairunnisa

Paediatric

Ninik Asmaningsih Soemyarso

Lecturer and Consultant in Nephrology Division, Department of Child Health, Faculty of Medicine,
Universitas Airlangga/ Dr. Soetomo General Hospital, Surabaya, Indonesia

Risky Vitria Prasetyo

Lecturer and Consultant in Nephrology Division, Department of Child Health, Faculty of Medicine,
Universitas Airlangga/ Dr. Soetomo General Hospital, Surabaya, Indonesia

Published

2021-03-24

How to Cite

Chairunnisa, Ninik Asmaningsih Soemyarso, & Risky Vitria Prasetyo. (2021). The Correlation of Congenital Anomalies of The Kidney and Urinary Tract with Renal Function in Children. Indian Journal of Forensic Medicine & Toxicology, 15(2), 2148-2151. https://doi.org/10.37506/ijfmt.v15i2.14692