The Correlation of Congenital Anomalies of The Kidney and Urinary Tract with Renal Function in Children
Keywords:Kidney, Urinary tract, Children, CAKUT, GFR
Background: Congenital Anomalies Kidney and Urinary Tract (CAKUT) are the leading cause of kidney
failure in children and cause of 30-40% end-stage renal disease with obstructive uropathy as the main cause.
CAKUT obstructive type are: vesico uretric junction obstruction (VUJO), pelvic uretric junction obstruction
(PUJO), posterior uretral valve (PUV) and non-obstructive type are reflux, neurogenic and hypoplasia. The
aim of this study is to describe the effect of CAKUT on renal function in child.
Methods: Retrospective study from medical records of children with CAKUT at Dr. Soetomo General
Hospital, Surabaya, Indonesia from January 2013 - March 2018. The characteristic of sex, age range, type of
CAKUT and glomerulus filtration (GFR) value were recorded from medical record. Data processing using
descriptive analysis with SPSS.
Result: A total of 94 Children on CAKUT abnormalities, both boys and girl’s presentation equal 50%.
Median age 3.0 (minimum-maximum 1.0-15.0) year. The most common CAKUT type in male were VUJO
17 (36.2%) and in female neurogenic type 19 (40.4%). Median initial glomerular filtration rate 2.7 ml/
min/1.73 m2. Analysis of correlation between CAKUT and renal function p=0.072 (R2=0,03). From 94
children of CAKUT, only 12 (12.8%) patients have undergo surgical intervention.
Conclusion: CAKUT with dominant obstructive type was more common in male and non-obstructive type
in female pediatric patient. There was no significance correlation of GFR between obstructive and nonobstructive type.
How to Cite
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Re use and mixing of content policy- We follow Creative Commons Licence Policy. We follow CC BY. Please refer below for all details
This license lets others distribute, remix, adapt, and build upon our work, even commercially, as long as they credit us for the original creation.
- The journal allows readers to read, download, copy, distribute, print, search, or link to the full texts of its articles and allow readers to use them for any other lawful purpose.
- The journal allows the author(s) to hold the copyright without restrictions.
- The journal allows the author(s) to retain publishing rights without restrictions