The Impact Factors of Peripheral Diabetic Neuropathy Which is Along with Hyperglycemia, Hypercholesterolemia, and Hyperaggregation

Authors

  • Citra Amaniah Anhar
  • Yetti Hernaningsih
  • Puspa Wardhani, Soebagijo Adi
  • Mohammad Saiful Ardhi

DOI:

https://doi.org/10.37506/ijfmt.v15i2.14696

Keywords:

Determinant Factors, Peripheral Diabetic Neuropathy, Hypeglycecimia, Hypercholesterolemia, Hyperaggregation

Abstract

Objective: The prevalence of T2DM case in 2018 has increased by 10.9%. The majority of T2DM
patients often ignore some of the most important conditions to experience complications, which is
complications of PDN. This study aims to analyze the dominant factors in PDF patients with hyperglycemia,
hypercholesterolemia, and hyperaggregation. Material and methods: This research is a case control study
conducted from April to October 2020. The sample is 85 patients who have been confirmed to have PDN
by neurologists aged 40 - 65. Sampling was conducted at several hospitals in Surabaya with a purposive
sampling method. Data analysis was conducted in three stages, namely univariate analysis, bivariate
analysis and multivariate analysis. Results: 85 PDN patients who experienced hyperglycemia amounted
to 81%, hypercholesterolemia 81%, and hyperaggregation 67%. The dominant factor affecting the three
conditions (hyperglycemia, hypercholeterol, and hyperagregation) in this PDN patient was a history of
hypertension with a value of p = {(0.012); (0.007); (0.001)} and also a long period of suffering from T2DM
with p value = {(0.019); (0.025); (0.041)). Meanwhile, age, gender and regularity for treatment control were
not the dominant influencing factors. Conclusion: Suffered for a long time from T2DM and a history of
hypertension are the main determinants of peripheral diabetic neuropathy which is along by hyperglycemia,
hypercholesterolemia, and hyperaggregation.

Author Biographies

Citra Amaniah Anhar

Master programs Student of Basic Medical Science, Faculty of Medicine, Universitas Airlangga,SurabayaIndonesia

Yetti Hernaningsih

Assistant Professor of Department of Clinical Pathology, Faculty of Medicine, Universitas Airlangga
– Dr. Soetomo General Hospital, Surabaya – Indonesia

Puspa Wardhani, Soebagijo Adi

Lecturer of Department of Clinical Pathology, Faculty
of Medicine, Universitas Airlangga – Dr. Soetomo General Hospital, Surabaya – Indonesia

Mohammad Saiful Ardhi

Lecturer of Department of Neurology, Faculty of Medicine, Universitas Airlangga – Dr.
Soetomo General Hospital, Surabaya – Indonesia

Published

2021-03-24

How to Cite

Citra Amaniah Anhar, Yetti Hernaningsih, Puspa Wardhani, Soebagijo Adi, & Mohammad Saiful Ardhi. (2021). The Impact Factors of Peripheral Diabetic Neuropathy Which is Along with Hyperglycemia, Hypercholesterolemia, and Hyperaggregation . Indian Journal of Forensic Medicine & Toxicology, 15(2), 2174-2184. https://doi.org/10.37506/ijfmt.v15i2.14696