The Effects of Turmeric Extract (Curcuma longa) Loaded Hidrogels in Accelerating Wound Closure
Keywords:Carboxymethyl Chitosan, Curcumin, Hydrogels, Turmeric, Wound Healing
Background: Disruption to healing process results on longer healing duration from the timeline. Povidone
iodine and tulle are common management in wound care. The advance of industry in health sector and
the availability of natural ingredients in Indonesia provide opportunities for developing alternatives for
wound care. Turmeric (Curcuma longa) contains curcumin which is anti-inflammatory, antibacterial,
and antioxidant; it is good for wound healing. Hydrogel nanocomplexes of carboxymethyl chitosan can
maintain moisture in wound area and protect curcumin from hydrolysis. Objective: To analyze the potential
of turmeric extract loaded hidrogels in accelerating wound closur. Method: experimental research with
“post-test only control group design”. The sample consisted of 30 mice which were assigned into 5 groups.
Result: All experimental groups experienced a gradual decrease in wound length. The statistical test results
for groups II and III showed significant advantages compared to group IV (p<0.05). Meanwhile, group I
did not have significant differences in wound closure compared to group IV on day 1 and 3 (p>0.05), but it
had significant results (p<0.05) on day 5. Conclusion: Turmeric extract loaded hidrogels can accelerate the
reduction of wound length.
How to Cite
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Re use and mixing of content policy- We follow Creative Commons Licence Policy. We follow CC BY. Please refer below for all details
This license lets others distribute, remix, adapt, and build upon our work, even commercially, as long as they credit us for the original creation.
- The journal allows readers to read, download, copy, distribute, print, search, or link to the full texts of its articles and allow readers to use them for any other lawful purpose.
- The journal allows the author(s) to hold the copyright without restrictions.
- The journal allows the author(s) to retain publishing rights without restrictions