The Effect of Nitric Oxide Supplement Intake on the Value of Hematological Examination of Health Workers Exposed to Covid-19

Authors

  • Didik Dwi Winarno
  • Abdul Rohim Tualek
  • Noeroel Widajati
  • Juliana Jalaludin
  • Nuh Huda
  • Raden Khairiyatul Afiyah
  • ,Firman Suryadi Rahman

DOI:

https://doi.org/10.37506/ijfmt.v15i2.14706

Keywords:

Nitric oxide, hematology, Covid-19

Abstract

Objective: Examination of the diagnostic covid-19 gold standard with real time reverse polymerase chain
reaction (RT-PCR) is still limited, so that the initial hematological examination (leukocytes, lymphocytes,
neutrophils, platelets, hemoglobin, and neutrophil lymphocyte ratio (NLR) plays an important role in
monitoring the course of covid-19 disease Macrophages release nitric oxide (NO) to kill parasites NO
inhibits migration and adhesion of leucocytes to the endothelium. Metode: The research design used preexperimental with one group pre-post test, the total sample was 80 health workers who were exposed to
Covid-19, the independent variable was the provision of NO and the dependent variable was the result of
a hematological examination (leukocytes, lymposites, platelets, neutrophils, hemoglobin and NLR). The
intervention was given NO 500 mg mixed with warm water 250 cc, given 3 times a day for 5 days, data
analysis used the T-test with a significance value of a<0.05. Results: There is a difference in the results
of the pre and post-test hematology giving NO to the results of the examination of leucocytes a=0.001,
lymphocytes a=0.000, platelets a=0.000, neutrophils a=0.000, hemoglobin a=0.031, and NLR a=0.000.
Conclusion: Giving NO to health workers exposed to Covid-19 can improve the hematology and immune
systems to fight the corona virus.

Author Biographies

Didik Dwi Winarno

Student at Magister of Occupational Health and Safety, Public Health Faculty, Airlangga University, 60115,
Surabaya, East Java, Indonesia

Abdul Rohim Tualek

Lecture at Department of Occupational Health and Safety, Public Health
Faculty, Airlangga University, 60115, Surabaya, East Java, Indonesia

Noeroel Widajati

Lecture at Department of Occupational Health and Safety, Public Health
Faculty, Airlangga University, 60115, Surabaya, East Java, Indonesia

Juliana Jalaludin

3Lecture at Department of Environmental
and Occupational Health, Faculty of Medicine and Health Sciences, University Putra Malaysia, 43400 UPM
Serdang, Selangor, Malaysia

Nuh Huda

Lecture at Departement of Nursing, STIKES Hang Tuah, Surabaya, Indonesia

Raden Khairiyatul Afiyah

Lecture at Department of Nursing, Nursing and Midwifery Faculty, Nahdatul Ulama Surabaya University

,Firman Suryadi Rahman

Student at Faculty of Public Health, Universitas Airlangga

Published

2021-03-24

How to Cite

Didik Dwi Winarno, Abdul Rohim Tualek, Noeroel Widajati, Juliana Jalaludin, Nuh Huda, Raden Khairiyatul Afiyah, & ,Firman Suryadi Rahman. (2021). The Effect of Nitric Oxide Supplement Intake on the Value of Hematological Examination of Health Workers Exposed to Covid-19. Indian Journal of Forensic Medicine & Toxicology, 15(2), 2245-2251. https://doi.org/10.37506/ijfmt.v15i2.14706