Discovery of Therapeutic Targets and Potential Drugs to Fight Severe Acute Respiratory Syndrome Coronavirus 2 (SARSCoV-2): A Review

Authors

  • Arif Nur Muhammad Ansori

DOI:

https://doi.org/10.37506/ijfmt.v15i2.14731

Keywords:

COVID-19, drug discovery, SARS-CoV-2.

Abstract

SARS-CoV-2, the causative agent of COVID-19, has led to more than two million deaths worldwide. There
are currently no specific therapies approved to treat COVID-19 and drug repositioning, rather than new
drug discovery, which may be the best short-term option for controlling the pandemic. In this review, the
author discusses important viral targets such as the papain-like protease, RNA-dependent RNA polymerase,
3-chymotrypsin-like protease, and spike protein. The information about chemical compounds and targets
provided in this review will aid further in vitro and in vivo studies to discover drugs to treat COVID-19.

Author Biography

Arif Nur Muhammad Ansori

Doctoral Student, Doctoral Program in Veterinary Science, Faculty of Veterinary Medicine, Universitas Airlangga,
Surabaya, Indonesia

Published

2021-03-24

How to Cite

Arif Nur Muhammad Ansori. (2021). Discovery of Therapeutic Targets and Potential Drugs to Fight Severe Acute Respiratory Syndrome Coronavirus 2 (SARSCoV-2): A Review. Indian Journal of Forensic Medicine & Toxicology, 15(2), 2396-2401. https://doi.org/10.37506/ijfmt.v15i2.14731