Estimation of Lepitn, Melatonin , and Adropin Hormones in Gestational Diabetes Mellitus (GDM) in Tikrit City

Abstract

The increased incidence of gestational diabetes (GDM), and its negative effect for the mother, and the
fetus imposes the need to study the mechanisms which resulting in pregnancy complications development.
This study was carried out to study the relationship between (GDM) and some hormones levels (liptin,
melatonin, and adropin) in the three semester of pregnant women’s, also estimation of (glucose, and lipid)
profil). the study included (90) pregnant women divided to three groups (1st semester, second semester, and
trimester) (30) women for each group. Also the study included (30) non infected women with (GDM). The
results showed significant increase of leptin, and adropin(p?0.05) in first semester comparative with second
and third semester and control group. There was significant decrease of melatonin in GDM comparative to
control group. The level of lipid profile elevated in (GDM) comparative to non.