Preparation, Characterization, Antibacterial Study, Toxicity Study of New Phenylene diamine- Formazan Derivatives

Abstract

Formazans are known to be characterized by containing very effective functional groups that have an effect
on the possession of any compound with a pharmaceutical and biological characteristic as antimicrobials
for many microbes, as these compounds have proven high resistance to the spread of cancerous tumors and
the spread of bacteria and fungi. Series of formazan derivatives were synthesized in this study from metaphenylene diamine via imination reaction then coupling reaction to yield new five derivatives. The formatted
formazan derivatives have been investigated through various instrumental -spectral techniques represented
by (I.R- Infrared spectra ,H. NMR -Proton magnetic resonance , Mass -Spectra )– as a spectrophotometric
measurements ,then bio- studying via various bio- experiments in this field like cytotoxicity, resistance of
anti-bacteria.