Effect of Oxymetholone on The Sperm Quality and Sex Hormone Profile in Male Rats

Authors

  • Zahraa Lateef Abd
  • Bushra Abbas alzubaidi

DOI:

https://doi.org/10.37506/ijfmt.v15i2.14926

Keywords:

Oxymetholone, sperm parameters, hormonal profiles.

Abstract

The objective of present study was to evaluated the effect of Oxymetholone drug on sperm parameters
and sex hormone in adult male rats. Twenty male rats sexually mature were randomly divided into two
groups; Each group has 10 rats. The treated group administered orally with Oxymethololne drug 5 mg/g
body weight/ day of for 60 days while the control group administered orally normal saline per day. SPSS
analysis of data generated with P< 0.05 considered statistically significant. The results showed a significant
decrease (p <0.05) in the mean sperm count, the motility and viability in treated group compared to control.
Also, LH (luteinizing hormone) FSH (follicle stimulating hormone) and T (testosterone) of the treated group
were significantly lowered compared to the control. The administration of Oxymethylene induces low sperm
quality with reduction in sex hormone.

Author Biographies

  • Zahraa Lateef Abd

    Researcher, Part of Thesis, Department of Biology ,Faculty of Education for Girls, Kufa University, Iraq

  • Bushra Abbas alzubaidi

    Professor, Ph.D, Biology Department, Faculty of Education for Girls, Iraq

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Published

2021-03-24

Issue

Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology

Section

Articles

License

https://creativecommons.org/licenses/by-nc/2.0/deed.en

How to Cite

Effect of Oxymetholone on The Sperm Quality and Sex Hormone Profile in Male Rats . (2021). Indian Journal of Forensic Medicine & Toxicology, 15(2), 3557-3562. https://doi.org/10.37506/ijfmt.v15i2.14926