Study the Negative Effects of Pseudoephedrine on Brain Tissues in Adult Albino Male Rats
Keywords:nervous system, pseudoephedrine, brain tissue, male rats.
In this study, (24) male animals were used, which were divided randomly into four groups. Each group
included (6) animals, which are: the control group that was given drinking water and food daily, and the
group of rats treated with pseudoephedrine at a dose of (40) mg / Kg of body weight for a period of (30)
days, the group of rats treated with pseudoephedrine at a dose of (40) mg / kg of body weight for a period
of (40) days, the group of rats treated with pseudoephedrine at a dose of (40) mg / kg of body weight for a
period of (50) days, the animals dosed the drug by the oropharyngeal tube at a dose of (1) ml, and after the
end of the experiment, the animals were scarified , brain samples were taken and preserved with formalin
at a concentration of 10% until the tissue sections were made, when the meningeal membrane appeared the
upper layers of the cerebral cortex in the group treated with pseudoephedrine for a period of 30 days were
close to normal, while the group treated with pseudoephedrine for a period of (40) days showed shrinkage
in the deep layers of the cerebral cortex and hemolysis in many blood vessels, and the meningeal membrane
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