Clinical important of E-Cadherin, CA15-3 and CEA in Diagnostic and Flow Up for Breast Cancer Patients
Keywords:CA15-3, CEA, E-cadherin, MUC-1, CEA
Background: The normal prevailing cancer in the women is Breast cancer, other than nonmelanoma skin
cancer. E-cadherin performs an essential role in epithelial cell adhesion and the decline of its role is the main
donor to cancer rise because the majority of solid tumors are carcinomas that occur from epithelial tissue. A
segment of the mucin-1 (MUC-1) is the cancer antigen 15-3 (CA15-3) order of glycoproteins, is classified
as a serviceable tumor marker inspired by revised glycosylation of itself. The carcinoembryonic antigen
(CEA) levels is raise in the blood, as a sort of cell adhesion molecule are associated with tumor metastasis.
Methods A cross-sectional study held implemented on100 specimens, 50 patient with breast cancer ere and
subsequent chemotherapy therapy with 50 healthy individuals (healthy patients).
Results The result reveals significant disparities patient group the same patient as a novel cause, following
initial chemotherapy procedure and matched with the control group in some tumors markers such as (CA15-
3, CEA) exact (E-cadherin) shows non-significant.
Conclusions Our cross-sectional study designates that the E-Cadherin was non-significant for breast cancer
patients including Tumors markers (CA15-3, CEA) bestows significance with breast cancer patients.
How to Cite
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Re use and mixing of content policy- We follow Creative Commons Licence Policy. We follow CC BY. Please refer below for all details
This license lets others distribute, remix, adapt, and build upon our work, even commercially, as long as they credit us for the original creation.
- The journal allows readers to read, download, copy, distribute, print, search, or link to the full texts of its articles and allow readers to use them for any other lawful purpose.
- The journal allows the author(s) to hold the copyright without restrictions.
- The journal allows the author(s) to retain publishing rights without restrictions