Round Cell Tumors - Classification & Overview
Keywords:Small round blue cell tumors, Ewings/PNET, Rhabdomyosarcoma, Wilm’s tumor, Lymphoma, NUT (Nuclear protein in testis) carcinoma
Round cell tumors from time indefinite have been affecting mankind, not only by their dangerous and life
threatening nature but also by their vast variety. Number of tumors share similar histology, composed of
relatively uniform primitive Small Round Blue Cells. They also share many demographic, radiographic
and clinical similarities, which often lead to misinterpretation and wrong diagnosis. These tumors, although
sharing similar looks which is quite confusing, come from different origin, in different sizes, colors, site of
action & most importantly nature. A few are aggressive and others are latent and benign. In some cases the
etiology is known, however on the other hand a large number of these tumors have an idiopathic etiology.
Whatever the lesion or however the appearance clinically, histopatholgically or cytologically, these round cell
tumors, continue to fascinate and confuse us & lack of a proper classification adds to the misinterpretation.
This review article is thus an attempt to go through this vast variety of tumor thoroughly along with an
attempt to provide a proper classification for the tumor itself.
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