A Clinical Study about the Biochemical Changes in the Pleural Liquid During Chemotherapy Against Ovarian Cancer
Keywords:Ovarian cancer, chemotherapy, pleural effusion, biochemical markers
Ovarian cancer (OC) is one of the major causes of cancer deaths among women. Owing to the retrieval
effects of platinum based chemotherapy among the ovarian cancer patients, objective of this report was
to assess the effects of the first round of chemotherapy among women with ovarian cancer. Here, the
levels of the pleural markers for the lipid profile and the cancer bio markers, before and after the cis-platin
based chemotherapy were tested among ovarian cancer patients. The biochemical indices may be of use in
deciphering the relation between cancer relapse and platinum retrieval. The pleural analyses pre and post
platinum chemotherapy session demonstrated wide range of biochemical and protein marker changes among
ovarian cancer patients. However, the pleural thickness and the pleural levels of the cancer biomarkers
were not impressively reduced after the first cycle of chemotherapy. Hence, our data can be considered
as a pavement for the discovery of further markers in the pleural liquid as well as a reliable monitor for
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