Antiplatelet therapy in Coronary Artery Disease
Keywords:antiplatelet; coronary artery disease; thrombosis; aspirin; clopidogrel
Coronary artery disease (CAD) is the leading cause of morbidity and mortality worldwide. Platelets play
crucial role for the development of thrombus in the atherosclerotic narrowed arteries. This review article
summarizes modern antiplatelet therapies particularly, aspirin and clopidogrel in coronary artery disease,
platelet aggregation, possible risk factors, their mechanism of action and pharmacological properties. In
addition, it provides up to date information regarding acetyl salicylic acid - aspirin and representative of the
thienopyridine – clopidogrel and their role in patients with CAD.
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