Analysis of Powder Properties and Pharmacopeial Spesifications of Bagasse Cellulose Isolated from Saccharum Officinarum L in Indonesia

Authors

  • Begum Fauziyah
  • Mohammad Yuwono
  • Isnaeni

DOI:

https://doi.org/10.37506/ijfmt.v15i3.15634

Keywords:

: Powder Properties, Pharmacopeial Spesifications, Bagasse Cellulose, Saccharum Officinarum L

Abstract

Saccharum Officinarum L is native to Asian countries, including Asia. Indonesia is the third-largest sugarcane
producer in the ASEAN region. The amount of sugarcane production represents the potential amount of
bagasse waste obtained. Bagasse has not been used properly and optimally in Indonesia. Bagasse contains
43.6% cellulose; hemicellulose 33.8%; lignin 18.1%; ash 2.3% and wax 0.8%. The purpose of this study
was to isolate bagasse cellulose with 5% of nitric acid. We determined the organoleptic powder properties
and pharmacopeial specifications of bagasse cellulose as pharmaceutical raw materials. As a result, the test
parameters as pharmaceutical raw materials for bagasse cellulose met the requirements compared to Japan
Pharmacopeia XV except for the ash content value. Bagasse cellulose powder had a white color, a water
content of 5.93%, and pH 6.7. It was insoluble in water-ethanol and ether and had Pb-Cr-Cd metal content
<10 ppm. The microbial limits were below the specified requirements. The ash content was 0.6, the bulk
density was 0.136, the tapped density was 0.158, Carr’s index was 13.92, the Hausner ratio was 1.162, and
the angle of repose was 56.4. Based on the angle of repose value, bagasse cellulose powder had fairly good
flow properties.

Author Biographies

Begum Fauziyah

Doctoral Program of Pharmaceutical Science, Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia

Mohammad Yuwono

Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia

Isnaeni

Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia

Published

2021-05-17

How to Cite

Begum Fauziyah, Mohammad Yuwono, & Isnaeni. (2021). Analysis of Powder Properties and Pharmacopeial Spesifications of Bagasse Cellulose Isolated from Saccharum Officinarum L in Indonesia. Indian Journal of Forensic Medicine & Toxicology, 15(3), 2154-2163. https://doi.org/10.37506/ijfmt.v15i3.15634