The Role of Reactive Oxygen Species and Bacterial Infections in Male in Male Infertility in Al- Anbar Province / West of Iraq

Authors

  • Dhuha A. Abbas
  • Abbas O. Al.janabi
  • Waleed N.

DOI:

https://doi.org/10.37506/ijfmt.v15i3.15635

Keywords:

Male infertility, ROS, Bacterial infection

Abstract

In the male genital tract, spermatozoa and leukocytes, including neutrophils and macrophages, generate
reactive oxygen species (ROS). ROS is involved in the regulation of sperm functions, such as acrosome
reactions and capacitation. Infections result in excessive ROS production, resulting in a ‘oxidative burst’
of neutrophils/macrophages as a first-line defense mechanism. During infection, the imbalance of pro-and
antioxidants favoring the former results in oxidative stress that impairs the sperm functions mentioned In
addition to motility and fertilization. ROS produced during testis and epididymis infections is especially
harmful to sperm due to longer contact time and lack of antioxidant protection. Only very high numbers of
ROS-producing leukocytes are harmful to sperm functions in the final ejaculate.

Author Biographies

Dhuha A. Abbas

Assistant Lecturer, Bacteriology Department, Falluja Teaching Hospital, AL-Anbar Province, Iraq,

Abbas O. Al.janabi

Assistant Prof., Microbiology Department, College of Medicine, University of Anbar, Iraq

Waleed N.

Prof., Surgery
Department, College of Medicine, University of Anbar, Iraq

Published

2021-05-17

How to Cite

Dhuha A. Abbas, Abbas O. Al.janabi, & Waleed N. (2021). The Role of Reactive Oxygen Species and Bacterial Infections in Male in Male Infertility in Al- Anbar Province / West of Iraq. Indian Journal of Forensic Medicine & Toxicology, 15(3), 2164-2169. https://doi.org/10.37506/ijfmt.v15i3.15635