Study the Effect of Hypercholestrolemic Diet on the Histological Changes of the Kidneys in Local Male Rabbit Oryctolagus cuniculus
Keywords:hypercholestrolemic diet, kidneys, male rabbit, Oryctolagus cuniculu
The presented work is conducted to examine the impact of hypercholestrolemic diet on male rabbits’
kidneys. A total of 10 male and adult rabbits have been divided (randomly) into 2 groups (5/group) for three
months, while the first group was allowed to ad labium supply and drinking tap water and was termed as the
control group (G1). Second group rabbits have orally administrated 1,5% gm of the cholesterol with the diet
throughout the 3 months (G2). This work indicated the occurrence related to tissue changes in the kidney
tissue compared with the control group.
Conclusion: In conclusion, our study showed that the hypercholestrolemic diet at a dose of 1.5% gm caused
pathological changes to the kidney tissue such as fatty changes in the tissue, the presence of fatty droplets
within the capillary of the glomerulus, inflammatory infiltration of cells in the interstitial tissue of the kidney,
cystic expansion of the renal tubules, and addition to the presence of hemorrhage compared to the control
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