Study of Some Physiological and Histological Parameters of Albino Rats Administrated with a Herbal Obesity Slimmer Product

Abstract

The modern studies on the treatment of obesity have dedicated on the potential activity of plants to control
obesity on the metabolism of lipid and glucose. The aim of this study is to investigate about the effect of
AB slim on body metabolism of its – takers and determine its safety. 16 female rats (150 - 250) divided
equally into 4 groups, the first group considered as control group and administered distilled water, the three
other groups daily administered the prepared aqueous solution of AB slim capsule for 45 days. The animals
weighed after 24 hr. of the last administration, the animals were weighed. The results showed after weeks of
treatment that the animals gain weight instead of losing it and there were no beneficial effects of this remedy
on lipid profile, in contrast there was an increase in LDL levels and decrease in HDL. The hisopathological
study showed degeneration and necrosis in most organs , liver, kidney, spleen and gastrointestinal tract.