Effect of Sonchus oleracea Extract on Some Virulence Factor of Klebsiella pneumonia Which Isolated from Urinary Tract Infection in Ramadi Hospital
Keywords:of Sonchus oleracea extract, virulence factor of klebsiella pneumonia
Background: The plant contains vitamin C, thiamin, riboflavin, and some citrus and saponins. Medical
benefits of wrapping Its medicinal benefits are attributed to the similarity between it and chicory Tonic and
regulator of sugar level in The blood is a diuretic, a strong purgative, lowers the level of cholesterol in the
blood and combats scurvy, as it is anthelmintic Methodology: Klebsiella bacteria were isolated from patients
suffering from urinary tract infections in Ramadi General Hospital in selective media (Maconkey Agar),
four concentrations of the aqueous and alcoholic extract were made 10%, 20%, 30 % and 40% to test the
effectiveness of the extracts in inhibiting growth and virulence factors for bacteria. Result: the effect of the
aqueous and alcoholic extracts of the Sonchus oleracea extract on the production of the biofilm of Klebsiella
bacteria, where it was observed that there were significant differences in the concentrations of the aqueous
and alcoholic extract in reducing the production of the biofilm of the bacteria, and the best concentration of
the aqueous and alcoholic extract was 40%, where the biofilm concentration was 31 compared to the rest
of the concentrations 3%, 20% and 10%, where its concentration reached .55, .64, and .74, respectively,
and compared to the control, where its concentration was .98%. It was not noted that there were significant
differences between the concentrations of plant extracts and aqueous and alcoholic extract in Reducing
biofilm yield. conclusion the results explain that this plant has many It is one of the effective compounds
such as vitamin C, thiamin, riboflavin, and some citrus and saponins. That destroy the cell wall and thus
reduce the production of the biofilm and that these compounds increase by increasing the concentration of
plant extracts, and this explains the effect of the high concentration in reducing the production of the biofilm.
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