The Effect of Iron Nanoparticles (FeNPs) on Some Biological and Hematological Parameters in Albino Rats
Keywords:Iron Nanoparticles, Biological and hematological, Rats.
Background: Nowadays, iron nanoparticles and other nanomaterials are widely used in many fields
including industrial and biomedical fields. Yet many concerns remain about their fate and toxicity to living
Objective: The aim of the current study was to evaluate the risk of using iron oxide nanomaterials as food
additives for animals to increase its utilization compared to bulk size particles of the same material.
Materials and Methods: The study included the effect of two different nano-sized iron oxides (25 nm and
50 nm) at two doses (1 mg/kg feed and 10 mg/kg feed) on some biological and hematological parameters in
male albino rats.
Results: The results indicate that rat’s performance, growth, feed conversion rates were not affected with
no sign of toxicity. Most of the hematological parameters in all treated groups were not affected by IONPs
except one group which showed a significant difference in the percent of granulocytes compared with the
Conclusion: It can be concluded that iron oxide NPs of different sizes and doses did not affect their
performance, growth rate, hematological parameters with no sign of toxicity.
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