Space Occupying Lesion- Uncovering the Hidden Pathology of the Brain: A Case Report

Abstract

Sudden deaths as a result of undiagnosed primary intra-cranial lesions are the rarest of rare. A brought dead
case of 32-year-old female with past history of headache without any clinical diagnosis was found to be the
case of “transitional meningioma with focal rhabdoid differentiation which is histo-pathologically classified
as WHO Grade 1 intra cranial lesion1. A complete autopsy including gross findings, internal findings with
histopathology and immuno-histochemistry can help us to diagnose the missed pathology to conclude the
cause of death. It will also give the idea about autopsy-based statistics of these rare intra-cranial lesions
which would help us to focus the cases with the history of headache to diagnose early with interventions and
investigation including MRI or CT scan during life.