A Review: Quorum Sensing Phenomenon: Regulation of biofilm in Pseudomonas aurogenosa

Authors

  • Rawa Abdul Redha Aziz
  • SuraAlaa Saud
  • Elaf Sameer Mohameed

DOI:

https://doi.org/10.37506/ijfmt.v15i3.15911

Keywords:

Cystic Fibrosis, Type IV pili (TFP), Alginate, Quorum sensing

Abstract

It is been mentioned that Pseudomonas aeruginosa, a ubiquitous, gram negative, can infect patients with
Cystic fibrosis. Treatment of infections can often be difficult due to its ability to produce biofilm. It has been
revealed that biofilms are enclosing architecture that would consist of planktonic cells to survive in harsh
environments. Biofilm is usually comprised of Pel, Psl, and Alginate, and many others to make a scaffold
that bacteria can attach and start making microcolonies. The formation of the biofilm and Alginate layer is
shown to be controlled by intricate cell-to-cell communication known as quorum sensing (QS). Finally, in
this report, we have taken the basic principles of what is P.aerogenosa, and how it is related to the cystic
fibrosis disease. Also, we have illustrated the formation of biofilms and the regulation of biofilms to the
quorum sensing LasR/LasI and RhlR/RhlI systems.

Author Biographies

Rawa Abdul Redha Aziz

Doctor Lecturer;Al-Karkh University of Science,College of Science, Department of Microbiology, Iraq

SuraAlaa Saud

Lecturer Asisstant; Al-Karkh University of Science,College of Science, Department of Microbiology, Iraq

Elaf Sameer Mohameed

Lecturer Asisstant; Al-Karkh University of Science,College of Science, Department of Microbiology, Iraq

Published

2021-05-17

How to Cite

Redha Aziz, R. A. ., Saud, S. ., & Mohameed, E. S. . (2021). A Review: Quorum Sensing Phenomenon: Regulation of biofilm in Pseudomonas aurogenosa. Indian Journal of Forensic Medicine & Toxicology, 15(3), 3934-3939. https://doi.org/10.37506/ijfmt.v15i3.15911