Correlation between Blood Group Phenotypes and Incidence of Helicobacter pyloriInfection

Authors

  • Shaymaa Hasan Abbas
  • Sura Abbas Khdair
  • Noor Wafaa Hashim
  • Lubab Tarek Nafea
  • Yasmeen Jamal Ali
  • Farah Nazar Mahmood

DOI:

https://doi.org/10.37506/ijfmt.v15i3.15962

Keywords:

Helicobacter pylori, ABO phenotypes, age, Rh factor

Abstract

Introduction: Helicobacter pylori is a gram-negative, spiral and flagellated bacteria.Thisinfection might
be present in more than 50 percent of people in the world.It has been found for several years that gastric
carcinoma occur more frequently in patients with blood group A, while duodenal ulcer had been associated
with blood group O.
Methodology: This is a prospective randomized controlled study in which patients who were newly diagnosed
with H. pylori infectionsincluded. Sixty-one, selected Iraqi patients were (37 female and 24 male), with age
ranges between (17-70) years. The Patients who enrolled in this study were divided according to (ABOBlood groups) into four groups.Data were collected from the patientsthrough direct interview included the
age, gender, history of the disease, blood group, and Rhesus (Rh) factor.
Results: In this study thelargest proportion(42.62%) of H. pylori infected patients according to ABO
phenotypes was found in blood group O, and the smallest proportion(8.2%) was in blood group AB. Though
the mean age of H. pylori infected patients in blood group O was higher than the other blood groups and less
mean age was in blood group B.The female patients exhibited greater percentages of H. pylori infection than
males for blood groups A, blood groups B, and blood group AB except for O blood groups patients where
proportion of male was more than female. On the other hand the percentage of H. pylori infected patients
in this study according to Rh factor distributed as follow: in +Rh factor (78.69%) and -Rh factor (21.31%).
Conclusion:The incidence of H. pylori infection is high in patients with blood group O so, the blood group
phenotypes may play a role in H. pylori infection. Meanwhile there was no correlation between age, and
Rh status with distribution of H. pylori infection among different ABO phenotypes patients.However, larger
sample size is needed to further clarify this association.

Author Biographies

Shaymaa Hasan Abbas

Assistant lecturer, Department of Clinical Pharmacy, College of Pharmacy, Mustansiriyah University, Baghdad,
Iraq, 

Sura Abbas Khdair

Assistant lecturer, Department of Clinical Pharmacy, College of Pharmacy, Mustansiriyah University, Baghdad,
Iraq

Noor Wafaa Hashim

Assistant lecturer, Department of Clinical Pharmacy, College of Pharmacy, Mustansiriyah University, Baghdad,
Iraq,

Lubab Tarek Nafea

Assistant lecturer, Department of Clinical Pharmacy, College of Pharmacy, Mustansiriyah University, Baghdad,
Iraq,

Yasmeen Jamal Ali

Teaching Assistant at College of Pharmacy, Mustansiriyah University, Baghdad, Iraq

Farah Nazar Mahmood


Teaching Assistant at College of Pharmacy, Mustansiriyah University, Baghdad, Iraq

Published

2021-05-17

How to Cite

Shaymaa Hasan Abbas, Sura Abbas Khdair, Noor Wafaa Hashim, Lubab Tarek Nafea, Yasmeen Jamal Ali, & Farah Nazar Mahmood. (2021). Correlation between Blood Group Phenotypes and Incidence of Helicobacter pyloriInfection. Indian Journal of Forensic Medicine & Toxicology, 15(3), 4263-4268. https://doi.org/10.37506/ijfmt.v15i3.15962

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