Perfusion -Weighted Magnetic Resonance Imaging Techniques and Protocols in the Evaluation of Cerebral Blood Flow, Blood Volume, and Vascular Permeability of Brain Neoplasms

Abstract

Objective : To identify the efficiency of perfusion, weighted magnetic resonance imaging techniques and
protocols in, evaluation of cerebral blood, flow, blood volume, & vascular, permeability of a tumor in the
brain in correlation with viability of brain neoplastic tissues.
Material and Methods : One hundred and fifteen patients with histologically proven brain tumors were
examined by 1.5 Tesla PHILIPS MR System. For four months, patients who were referred in an MRI
assessment were included in this review. Conventional MRIs protocol, (axial T2WI (TSE), Axial T1WI
(FSE), axial T2WI FALIR, axial T1WI post contrast). PW-MRI protocol axial Fast Echo –Echo Planner
Image (FE-EPI) Neuro-T2
* Perfusion Dynamic Contrast Enhancement agent (DCE-MRI), (Gadolinium(Gd)
contrast Magnevist).
Results and discussion: Magnetic Resonance Imaging in (10) patients (8.70%) revealed feature consistent
with brain tumors (control cases), the brain has been evaluated by routine study or conventional (protocol
C). (105) patients (91.3%) underwent examination with PW-MRI (FE-EPI) Neuro-T2* Perfusion (DCEMRI)
( protocol P). (18) patients (15.65%) with the anaplastic astrocytoma WHO grade (III), (17) patients
(14.78%) with metastatic brain tumors, (15) patients (13.04%) with non-recurrence of post-operative brain
tumors, (11) patients (9.57%) with high grade glioma, (10) patients (8.70%) with craniopharyngioma, (9)
patients (7.83%) with glioblastoma multiform WHO grade IV, (9) patients (7.83%) with low grade glioma,
(8) patients (6.96 %) with meningioma, the agemistocytic astrocytoma WHO grade(II) was the lowest
diagnosed brain tumor (2.61%).